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KMID : 1037120130310030215
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The World Journal of Men′s Health
2013 Volume.31 No. 3 p.215 ~ p.219
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Can the Mean Platelet Volume Be a Risk Factor for Vasculogenic Erectile Dysfunction?
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Ciftci Halil
Yeni Ercan
Demir Mehmet
Yagmur Ismail
Gumus Kemal
Celik Hakim
Savas Murat
Gulum Mehmet
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Abstract
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Purpose: The mean platelet volume (MPV) is a marker of the platelet activity and is reported to increase in vascular diseases. We aimed to investigate the association between MPV and vasculogenic erectile dysfunction (ED).
Materials and Methods: MPV and platelet (PLT) levels were measured in 50 cases of ED and 40 healthy controls. The diagnosis of vasculogenic ED was based on a detailed sexual history, physical examination, laboratory assessment, and color Doppler ultrasonography. The results are given as mean±standard deviation of the mean.
Results: The mean ages of the patient and the control groups were 53.70±12.39 years (range 24∼77 years) and 53.85±9.5 years (range 30∼73 years), respectively (p=0.947). The MPV and PLT values were significantly higher in the patients with ED than those of the controls (7.49±1.4), (6.85±1.2), (262.97±68), (252.89±82) respectively, p＜0.001). However, the MPV values were not statistically significantly different in the patients with severe ED according to the International Index of Erectile Function than in those with mild ED, p＞0.05), and there was no correlation between MPV and either age of patients (p=0.905) or duration of ED (p=0.583).
Conclusions: The platelet count and MPV was detected to be increased in patients with vasculogenic ED. This finding suggests a role for platelets in the pathogenesis of vascular complications and that the MPV would be useful in monitoring disease progression.
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KEYWORD
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Erectile dysfunction, Impotence, vasculogenic, Platelet
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